Does Pepcid affect the liver?

The effects of hepatic disease on the pharmacokinetics of the histamine H2-receptor antagonist famotidine were studied in seven healthy volunteers and 20 patients with chronic liver disease. Thus, famotidine had no effect on hepatic hemodynamics or function in healthy subjects and patients with chronic liver disease.Click to see full answer. Then, can Pepcid elevated liver enzymes?H2 receptor antagonists can rarely cause idiosyncratic drug reactions leading to acute hepatitis. Famotidine, however, is considered a relatively safe drug with regards to hepatotoxicity. The acute rise in liver enzymes made us consider an adverse drug reaction and famotidine was discontinued.Also, what are the side effects of long term use of famotidine? Famotidine side effects Adult side effects can include: headache. dizziness. constipation. diarrhea. Children under one year of age may also experience: agitation, unusual restlessness, or crying for no clear reason. In this way, can famotidine cause liver damage? Outcome and Management. The hepatic injury caused by famotidine is usually rapidly reversible with stopping the medication (Case 1). Famotidine has not been definitively linked to cases of acute liver failure, chronic hepatitis, prolonged cholestasis or vanishing bile duct syndrome.Are antacids bad for your liver?The researchers concluded that there is an association between PPI use among people who abuse alcohol and risk of liver disease. However, even non-PPI-based antacids (e.g., Pepto-Bismol, Tums, or H2 blockers such as Tagamet and Zantac) still suppress gastric acid to a lesser degree.